Dog Noise Anxiety and Big Pharma’s Newest Treatment – Not Recommended

Big Pharma’s newest ‘treatment’ for dog noise anxiety – ‘SILEO’ (dexmoedetomidine oromucosal gel), is made by Zoetis, a large pharmaceutical company that supplies many drugs to the veterinarian industry.

SILEO is the latest in a series of conventional anti-anxiety drugs Big Pharma has migrated from human use, to use for dogs. These drugs include Alprazolam (Xanax), Clomicalm (Clomipramine), Clonazepam (Klonopin), Diazepam (Vallium), and Reconcile (Prozac). Despite the dangers posed by the drug, Reconcile received FDA approval. And now SILEO.

The active ingredient in SILEO - dexmedtetomidine is a synthetic-chemical sedative (alpha-2 adrenoceptor agonist), first developed as a drug for humans, later migrated to use for dogs and cats.  Dexmedetomidine has 3 main clinical applications: (1) prolonged sedation in hospital settings; (2) general anesthesia, and procedural sedation; (3) dulling (obtunding) emergency delirium.

Most dog owners would prefer a happy dog to one that is anxious - whines, pants, paces, drools, and trembles with his/her heart racing. BUT is SILEO a beneficial option for an anxious dog? Let’s take a closer look, but before we do keep the following in mind…

Last week, Valeant Pharmaceuticals’ CEO, J. Michael Pearson stated “we’re in business of shareholder profit, not helping the sick” – the, “we’re” Mr. Pearson is referring to, is Big Pharma.

SILEO’s Ingredients

Active ingredient –

• Dexmedtetomidine hydrochloride

Inactive Ingredients –

• Hyprolose (hydroxypropyl cellulose, or HPMC) –
• Derived from wood pulp or another plant material such as corn, synthesized with propylene oxide.
• Cellulose - can cause gastrointestinal issues.
• Propylene glycol –
• A PEG compound that can be contaminated with ethylene oxide and 1, 4-dioxine both of which are carcinogens.
• Sodium Lauryl Sulfate (SLS) –
• Can be contaminated with ethylene oxide and 1, 4-dioxine both of which are carcinogens.
• Hydrochloric acid 10% -
• A corrosive.
• Sodium hydroxide 2M –
• An inorganic compound made from sodium hydroxide (caustic soda, lye) - skin, eye and mucous irritant, toxic by ingestion.
• Brilliant blue FCF (E133) –
• A food coloring is an allergen, toxin and carcinogen.
• Tartrazine (FD&C Yellow no 5, E102) –
• A food coloring is an allergen, toxin and carcinogen.
• Purified water

As you can see from the list above, SILEO contains multiple toxic, inflammatory ingredients that adversely affect the immune system, can damage gut health, and cause inflammation throughout the body. If a dog is exposed to these problematic ingredients once or twice in his/her lifetime, the negative impact on health is minimal. However SILEO is not designed or marketed as a ‘one time treatment’.  It is marketed as a treatment to be used on a repeated basis – whenever the ‘need’ arises. The same inactive ingredients in SILEO are used in a wide range of other products. Unless the dog’s owner is vigilant – the daily intake of these and similar toxins can quickly reach a critical mass. The inflammatory ingredients are also found in…

• Highly processed dry or canned dog ‘food’ and ‘treats’.
• Vaccines, which is just one of the reasons why it is so important to avoid over vaccination. (vaccination on an annual, two year, or 3 year vaccination ‘program’).
• Conventional OTC or veterinary prescribed flea, tick, heartworm preventatives.
• Other conventional drugs, including those used during surgery.
• Conventional, and many marketed as ‘natural’...
• Ear cleaners.
• Eye drops.
• Grooming products such as shampoo and oral ‘health’ products.
• Supplements.

SILEO Warnings

• ‘Impermeable’ disposable gloves should be worn to fill and handle the syringe, administer the drug, or when coming into contact with the dog’s mouth after application of SILEO.
• SILEO is not to be touched by pregnant woman as exposure – that includes simple contact of the drug on skin, can induce contractions and decrease fetal blood pressure.
• SILEO is absorbed by coming into direct exposure to skin, eyes, and mouth. In case of accidental exposure to eyes and content lenses you are supposed to rinse for 15 minutes and then seek medical advice immediately.
• Accidental exposure can cause sedation and changes in blood pressure. In case of accidental exposure you are to seek immediate medical attention.

There are more warnings listed for SILEO, the above is a sampling.

Are the alarm bells going off in your mind yet? 

Does this drug sound like something you want to place in your dog’s mouth?

In my opinion, SILEO is NOT a safe, nor is SILEO an ethical option for treating dog noise anxiety.

Dosing SILEO

• First step, put on those impermeable gloves.
• Second step, place the SILEO gel onto the mucosa between the dog’s cheek and gum. 

Scroll back up to the list of inactive ingredients – are you sure you want to put SILEO in your dog’s mouth?

SILEO Contradictions

Not for dogs with –

• Cardiovascular conditions
• Hypotension
• Respiratory conditions
• Liver or kidney disease
• Dogs in conditions of –
• Shock
• Severe debilitation
• Stress due to extreme heat
• Stress due to extreme cold
• Stress due to fatigue
• Dogs allergic to the active ingredient.
• More here.

Of course, Zoetis makes no mention of allergies to the inactive ingredients. Sileo is contradicted for the noted conditions because SILEO has adverse effects on the cardiovascular system, blood pressure, respiratory system, effects and burdens the liver and kidneys. SILEO might be a case of  'when the treatment' is worse than the condition being treated'.

Conclusion

Clearly SILEO has not been designed with a dog’s health uppermost in mind. Just another example of Big Pharma putting their shareholders’ profit first, and the health of a dog last.

I have had many rescued dogs in my own pack that come with extreme noise anxiety – including fireworks anxiety, gunshot anxiety, and thunder anxiety. I have taught many clients how to treat and remedy their dogs’ noise anxiety without the use of drugs.

If you want to treat and remedy anxiety using natural methods (which is what I recommend), a comprehensive approach includes working on becoming a ‘mind-full’ guardian to your dog.

You can start that process by:

• Learning about good stress, bad stress, and communication.
• Work on exercises for self-control, and better communication – this exercise is a good start.
• Learn to stop your dog’s pacing, and enable calm.
• Get your dog on a real food diet that supports optimal brain function, immune and gut health.
• Stop over-vaccinating, and clean-up your dog’s health care regimen.
• Make sure your dog gets structured exercise (physical and psychological) on a daily basis. Work on recall exercises.
• You can incorporate use of appropriate essential oils, or Bach flower essence.

You now have a plan to begin working on remedying anxiety naturally, without drugs.

Dogs don’t get to choose, we do! Don’t let your dog become a victim of Big Pharma and their partners in profit, veterinarians that prescribe and sell health deteriorating drugs - at the expense of your dog’s health and well-being.

For the love of dogs, pass it on.

Holistic Wellness and Behaviorist Services

Do you need holistic advice to support your companion animal's health and well being? Become a client. Book your consultation. My professional holistic nutrition, wellness and behavioral services are available to you:
🌿 Holistic Wellness Services for Dogs and Cats 🐕 🐈
🌿 Holistic Behaviorist Services for Dogs 🐕

My Holistic Client Services are Available Worldwide:
🇺🇸 USA
🇨🇦 Canada
🇬🇧 UK and other European countires
🇦🇺 Australia and other Oceania countires
🇭🇰 Hong Kong and other Asian countries
🇨🇷 Costa Rica and other Central American countries 
🇪🇺 European countries
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Available Holistic Consultations and Sessions:
📱 FaceTime
📱 Facebook video or voice calling
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📞 Phone
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Menu of Holistic Wellness Services for Dogs and Cats 🐕🐈
For more information go here.
✅  Maintain Health, and;
✅  Address Health Issues and Conditions:
✓ Treatment and Remedy 
✓ Pre-Surgery holistic support protocols
✓ Post-Surgery holistic healing protocols
✓ Pre-Vaccine holistic support protocols
✓ Post-Vaccine holistic support protocols
✓ Natural Insect and Parasite Prevention
✓ Natural Treatment for Insect, Parasite Infestation, Co-Infection, Disease
✅  Custom Designed Whole Food Diets - raw or gently cooked, and;
✅  Advice and Recommendation:
✓ Premade Diets - raw, dehydrated, freeze dried
✓ Supplemental Fresh Foods - raw, gently cooked
✓ Super foods
✓ Treats - raw, dehydrated, freeze dried, gently cooked
✓ Herbs
✓ Alternative Medicines

Menu of Holistic Behaviorist Services for Dogs 🐕
For more information go here.
In-person Sessions - available locally
Voice and Video Sessions - available worldwide
✓   Obedience Training
✓   Behavior Modification
✓   Psychological Rehabilitation

Affiliations to Companies
✓ None.
✓ I don't sell food or supplements.
✓ I'm not aligned with any companies.
✓ I choose to maintain my objectivity in selecting best-solutions for my individual client's needs.

Contact me
karen@ottawavalleydogwhisperer.ca

Article and graphics by Karen Rosenfeld

 

Dog Anxiety – Anxious Pacing, Hyper Activity - How to Stop It

Dog Anxiety – Anxious Pacing, Hyper Activity – how to stop it, and why you should stop it…

Anxious pacing, hyper activity – does your dog exhibit these behaviours? Maybe you have tried, or still are trying to tire your dog out with exercise - taking your dog for several long walks every day, play time with doggie friends, agility, fly ball and more. Even with all of this activity, nothing seems to tire your dog. You walk in the door, unclip the leash and your dog flies into the house, bounds off the furniture, and does not ‘settle down’.  Your dog might ‘ask’ to go back out, after he/she has just come in. You go to get ready to take your dog for his/her third walk of the day – your dog is pacing, jumping, whining. Or, maybe after a long day you finally get to sit down and relax – you’re about to read a book, watch a movie, or a program on television… and your dog will not settle down. Your dog gets up and starts to pace, or goes to look for something to ‘get into’, your dog brings you a ball, drops the ball in your lap, and begins to bark to tell you to ‘throw it’.  You have guests come over, or your children invite friends over – your dog is everywhere, dashing about, barking, pacing. You are exasperated – you’ve tried everything, yet nothing slows or settles your dog’s pacing – hyper activity.

Anxious Pacing - Why Does Your Dog Do This?

Well for a start your dog may have heightened sensitivity – an attribute that, when understood can be an amazing asset, but when misunderstood leads to no end of trouble for you, and your dog.  Anxiety, and stress may be compounded by other contributing factors, for example...

• You have heightened sensitivity.
• You and/or your dog has experienced an acute or chronic trauma.
• Your dog’s diet is not able to properly support his/her well being, etc.

The confluence of these circumstances can create a bad stress response in your dog, and you too!

The Daily Toll On You and Your Dog can Cause Long-Term Damage

Chronic stress is an inflammatory condition which can make your dog more vulnerable to inflammatory disease, degrade the quality of daily life, and shorten life-span. Stress has the same effect on us humans. 

Your Dog's Anxiety -Could it be a Gift, or Is It Just a Burden?

Dogs offer us humans many gifts - companionship, empathy, love, loyalty, joy and the opportunity to expand our humanity. If you adopt a dog that has acquired-anxiety, you will see further below that in order to help the dog, you must first help yourself - the rescue dog helps you, before you can help him/her. 

If you have had a dog since he/she was a puppy, and your dog develops anxiety, you may not realize it during the developmental phase of the condition but it is likely you have inadvertently contributed to the anxious state of your dog. To heal your dog of anxiety, you must first examine your own state of being, and you may need to do some healing. If it were not for your dog - the impetus to heal yourself may never have presented itself - your dog has given you a gift of immense value. Granted at the this time you may simple feel as if you have an immense burden - read on below, as when you do you will find the tools you need to unlock your dog's gift, and in so doing find healing for both you and your dog...

Anxious Pacing, Hyper Activity - Why is Your Dog experiencing this State?

Simply put – your dog does not know how to ‘self-regulate’- turn herself off, relax, and settle down. Heightened sensitivity if not properly supported can cause over-stimulation. Too much exercise can serve to over-stimulate your dog. Over excitement leads to over-stimulation. Not knowing how to confidently, normally cope with the ins and outs of daily life situations causes anxiety. Your dog’s concept of ‘normal’ is being in an excited state.

Three Types of Energy – Only two of Which Can be Expended with Exercise

I always say there are three types of physical energy that a dog may have to expend…

Energy Type 1

• Daily quota of normal physical energy that is typically expended via normal exercise such as going for daily walks.

Energy Type 2

• Stored-up energy which occurs of a dog is not getting the opportunity to expend daily energy on a regular basis.

Energy Type 3

• This energy is created by an unbalanced psychological state which creates physical energy.
• Think about how you feel when you are agitated
• You may have trouble sitting still, you may have difficulty concentrating, you may get up and pace, you may feel the need to otherwise expend energy, but if you are unable to resolve the real source of your stress, you will not be able to relax - even if you are exhausted. 
• It is the same for our canine companions. 
• To resolve the anxious pacing and hyper activity you must address the root cause – anxiety, and stress. 

So let’s take a look at how to remedy this curable situation…

How To Stop Anxious Pacing, Hyper Activity

Your dog needs you to take over decision making – you must show your dog what he/she must do, you must show your dog what 'normal' really is. Once you have properly mentored your dog, he/she will settle down – he/she will know how maintain a good stress response; that in turn provides the ground work for self-regulation. Before you can start to teach your dog self-regulation, remember that you need to learn how to self-regulate yourself. 

For the purposes of this exercise we will use the example of a dog that starts to pace at night just when his/her human has sat down to relax…

When night time rolls around, you are going to have to take over for your dog – you cannot leave any decision making up to your dog until he/she has learned how to cope. Meaning, he/she has had the opportunity to learn what he/she should do.

So, when you go to sit down to relax, and your dog starts to get agitated (likely exemplified by pacing back and forth, getting into ‘stuff’ etc.) do the following...

• Stop the pacing.
• When you sit down – indicate to him/her that he/she is to sit down.
• Assign a place for your dog to sit.
• Do not allow him/her to get up, and move elsewhere.
• You decide where he/she sits – you don’t allow your dog to decide.
• Your dog will try to get up – don’t be agitated by this, simply show your dog to sit back down.
• Open your senses, be observant but not intense - use your periphery vision, and hearing:
• Notice if your dog starts to pant.
• If your dog’s breathing escalates to panting, take a deep breath to ground yourself.
• If your dog starts to get up...
• Give your dog an audio cue like ‘Uh’
• Follow that immediately with a visual cue – put your hand in the air in-front of you with palm facing vertically up (stop symbol), and then turn your palm so it is facing up to indicate to him/her to sit back down, then sweep your palm in a downward motion to show him/her to lay down.
• When you first do this exercise, your dog may ignore your breath, your vocal cue, and your hand signals but do them anyway to give him/her the grace of choice to choose to respond.
• If he/she decides to ignore your cues, and instructions, and she gets up – you get up too, then calmly walk over to where he/she has gone...
• If he/she is pacing, take another deep breath, and then;
• Put the following thoughts in your min;
• “I am not upset at you, you simply need direction, no more pacing and anxiety, I have your back – this is what we are going to do”
• Then lightly but firmly do one of the following:
• ‘Still’ (stop) his/her pacing by touching his/her side with your fingers outstretched, sustain the touch, still yourself – this is what I call a ‘stilling touch’.
• Hold the touch for at least 5 seconds, after which you can take your other hand – draw two fingers up from his/her eyes to sweep outward towards where you would like your dog to go.
• If he/she does not respond to this by going to the place you have indicated, lightly grasp his/her collar (no tension in your hand, no force, just lightly). With two fingers on one side of the collar, and your thumb on the underside of the collar give his/her collar a quick little plucking motion in the direction you want him/her to go in.
• Don’t pull hard, and don’t do a sustained tug/pull for if you do you are indulging in an argument when what you really need to do is direct with respect.
• You do not want to force, or argue – you simply want to show what it is you want. 
• If he/she tries to wander off – simply take a deep breath, say ‘uh’ (audio cues to get his/her attention, and let him/her know you are directing).
• Walk calmly (normally) up to your dog, give him/her a quick tap on her side (do not linger the touch, do not push), then show him/her with your hand where you want your dog to go.
• If he/she decides not to go, take her lightly by the collar and give a slight pluck of the collar in the direction you want him/her to go, then immediately relax your grip on the collar, and let go of the collar completely.
• Use your hand to indicate to him/her to lie down.
• Then you go sit down, take another deep breath as you do. Use your thoughts to help ground you through the entire process – i.e. “this is your new normal, I have your back, I will direct you so you don’t have to be anxious – I will let you know what to do”

 Before you start the above exercise remember you want your dog to calm; what you want from your dog – you must first be yourself. This is the true meaning of consistency, which in-turn is a fundamental quality of leadership.

By doing the above you take 100% control of the situation…

• You put a structure in place, which is safe and comforting for your dog.
• In the process of doing the above, you work with your dog, your dog works with you - you create a situation of mutual respect. Your dog gets to work psychologically which is stabilizing, and fulfilling for your dog. 
• You maintain control of yourself first – you remain calm, grounded – which is what you want your dog to be. 
• You lead by true example – something dogs, (and humans) appreciate. A skill that will serve you well in many aspects of your life...
• Your dog's gift to you is realized.

Continue to do the above – don’t allow yourself to get sucked into the emotion of your dog’s anxious state. Remember your dog will try to return to his/her anxious state because she thinks that is normal. Just like we would do all we can to adhere to what we think of as normal – even if that ‘normal’ is an altered, and unhealthy state of normal.  Sometimes we need someone else to help us remember or learn what normal is

Guide your dog with true logic and he/she will embrace it. Wander off course yourself by becoming unstable (emotional), and you lead your dog to be unstable.

Every time your dog tries to get up, give him/her the cues so eventually he/she won’t bother to ‘go there’. Adhere the true meaning of consistent.

By doing the above you teach your dog how to embrace calm. This builds his/her confidence, helps to dispel his/her chronic anxiety, and eventually your dog will be in a position to make good choices without constant supervision from you.

Never let your dog pace. Pacing is anxiety, and the more he/she paces, the further he/she will escalate into a state of anxiety. You can use the above technique in all situations in which your dog becomes agitated. The more situations you apply this to, the faster you and your dog will learn to remain calm. Every situation in a typical day influences the next situation – use this to your advantage. And remember do as I do, be as I am – whatever you want your dog to do – you must first achieve that state yourself.

Holistic Wellness and Behaviorist Services

Do you need holistic advice to support your companion animal's health and well being? Become a client. Book your consultation. My professional holistic nutrition, wellness and behavioral services are available to you:
🌿 Holistic Wellness Services for Dogs and Cats 🐕 🐈
🌿 Holistic Behaviorist Services for Dogs 🐕

My Holistic Client Services are Available Worldwide:
🇺🇸 USA
🇨🇦 Canada
🇬🇧 UK and other European countires
🇦🇺 Australia and other Oceania countires
🇭🇰 Hong Kong and other Asian countries
🇨🇷 Costa Rica and other Central American countries 
🇪🇺 European countries
🇹🇹 Trinidad and Tobago and other South America countries
🇿🇦 South Africa and other African countries
🇸🇪 Sweden and other european countries
🇦🇪 United Arab Emirates

Available Holistic Consultations and Sessions:
📱 FaceTime
📱 Facebook video or voice calling
💻 Skype
📞 Phone
📧 Email 
🚶🏻‍♀️ In-Person

Menu of Holistic Wellness Services for Dogs and Cats 🐕🐈
For more information go here.
✅  Maintain Health, and;
✅  Address Health Issues and Conditions:
✓ Treatment and Remedy 
✓ Pre-Surgery holistic support protocols
✓ Post-Surgery holistic healing protocols
✓ Pre-Vaccine holistic support protocols
✓ Post-Vaccine holistic support protocols
✓ Natural Insect and Parasite Prevention
✓ Natural Treatment for Insect, Parasite Infestation, Co-Infection, Disease
✅  Custom Designed Whole Food Diets - raw or gently cooked, and;
✅  Advice and Recommendation:
✓ Premade Diets - raw, dehydrated, freeze dried
✓ Supplemental Fresh Foods - raw, gently cooked
✓ Super foods
✓ Treats - raw, dehydrated, freeze dried, gently cooked
✓ Herbs
✓ Alternative Medicines

Menu of Holistic Behaviorist Services for Dogs 🐕
For more information go here.
In-person Sessions - available locally
Voice and Video Sessions - available worldwide
✓   Obedience Training
✓   Behavior Modification
✓   Psychological Rehabilitation

Affiliations to Companies
✓ None.
✓ I don't sell food or supplements.
✓ I'm not aligned with any companies.
✓ I choose to maintain my objectivity in selecting best-solutions for my individual client's needs.

Contact me
karen@ottawavalleydogwhisperer.ca

Article and graphics by Karen Rosenfeld